P0300 on a 2022 Ford F 150 Super Cab Diesel

P0300 is a generic OBD2 powertrain code for random or multiple cylinder misfire. Unlike P0301 through P0308, it does not point to one specific cylinder, so the cause can be ignition, fuel, air, sensor, or mechanical.

Not your vehicle? See general P0300 info.

Most common causes on the 2022 Ford F 150 Super Cab Diesel

Ranked from 559 NHTSA owner complaints filed for this vehicle.

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1
Intake valve failure in the 2.7L EcoBoost engine (NHTSA recall 24S55)
High severity
Multiple owners describe an engine misfire warning with extreme vibration followed by catastrophic failure, traced by the dealer to a broken intake valve; Ford has an active recall (24S55) for this exact failure on 2021-2022 F-150s with the 2.7L EcoBoost.
Reported in 3 NHTSA complaints
2
Unresolved rough idle/near-stall under factory warranty
Medium severity
One owner reports persistent idle shudder and near-stalling that two dealerships could not diagnose or fix under warranty; worth a compression and fuel-trim check even with no stored trouble code found yet.
Reported in 1 NHTSA complaint
3
Worn or fouled spark plugs
Low severity
The most common overall cause of a random misfire code on any engine; check gap, wear, and fouling.
Common cause
Parts:spark plugs
4
Failing ignition coil(s)
Medium severity
A weakening coil-on-plug unit causes an intermittent or cylinder-specific misfire; one owner's engine was initially misdiagnosed as an ignition-coil fault before a valve failure was found, showing the two can look similar.
Common cause
Parts:ignition coil
5
Clogged or leaking fuel injector(s)
Medium severity
A dirty or leaking direct injector disrupts the air/fuel ratio on that cylinder.
Common cause
Parts:fuel injector
6
Carbon-fouled intake valves
Medium severity
Direct-injection turbo engines like this one don't wash the intake valves with fuel, so carbon buildup on the valves is a common misfire contributor over time.
Common cause
7
Vacuum/intake leak
Medium severity
Unmetered air after the MAF sensor causes a lean misfire; smoke-test intake boots and vacuum lines, especially around the turbo plumbing.
Common cause
8
EGR valve/passage fault
Low severity
A stuck or clogged EGR path disrupts combustion at idle and light load.
Common cause
Parts:EGR valve

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These causes are aggregated from NHTSA owner complaints and general repair knowledge — this is not a diagnosis. P0300 on your car still needs shop confirmation before any repair.

Common symptoms

Flashing or steady check engine light
Rough idle
Shaking under acceleration
Loss of power
Fuel smell from exhaust

What to check before replacing parts

Scan for cylinder-specific misfire codes

Look for: A companion P0301–P0308 pins the misfire to one cylinder — start there. P0300 with no cylinder code points at something hitting several at once: fuel pressure, a large vacuum leak, or timing.

Inspect the spark plugs and coils

Look for: Pull the plugs: black/sooty = rich, oily = oil intrusion, white/blistered = lean or overheating, cracked porcelain or an out-of-spec gap = replace. Then swap a coil to another cylinder — if a cylinder-specific code follows the coil, the coil is bad.

Check fuel trims for a vacuum leak

Look for: High positive short- and long-term trims (worst at idle, improving as RPM rises) mean unmetered air is getting in. Smoke-test the intake and listen for hissing.

Verify fuel pressure

Look for: Compare running/cranking pressure to the vehicle spec. Low or dropping pressure starves multiple cylinders and reads as a random misfire — suspect the pump, filter, or regulator.

Compression / leak-down test if ignition and fuel check out

Look for: A cylinder 15%+ below the others, or leak-down hissing from the intake (intake valve), exhaust (exhaust valve), or oil filler (rings), means the misfire is mechanical — not a swap-in part.

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Matching symptoms

Car Runs Rough Flashing Check Engine Light