P0300 on a 2015 Ford F 150 Super Crew

P0300 is a generic OBD2 powertrain code for random or multiple cylinder misfire. Unlike P0301 through P0308, it does not point to one specific cylinder, so the cause can be ignition, fuel, air, sensor, or mechanical.

Not your vehicle? See general P0300 info.

Most common causes on the 2015 Ford F 150 Super Crew

Ranked from 1,425 NHTSA owner complaints filed for this vehicle.

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1
Ignition coil failure
Medium severity
One owner documented a misfire diagnosed to melted ignition coils that had to be replaced four times before the PCM itself was found faulty — coil failure is a direct, confirmed misfire cause on this vehicle.
Reported in 1 NHTSA complaint
Parts:ignition coil
2
VCT (variable cam timing) solenoid fault
Medium severity
A documented VCT solenoid problem on this truck caused intermittent stalling after warm-up with no stored codes — cam-timing solenoid faults disrupt valve events enough to cause rough running/misfire-type symptoms.
Reported in 1 NHTSA complaint
Parts:VCT solenoid
3
Intake manifold runner control (IMRC) actuator failure
Medium severity
A premature intake manifold actuator failure (codes P2007/P2005) was reported on this exact vehicle; a stuck runner control disrupts cylinder airflow balance and can produce misfire-like rough running.
Reported in 1 NHTSA complaint
Parts:intake manifold runner control actuator
4
Worn or fouled spark plugs
Low severity
The single most common misfire cause overall; inspect for wide gaps, fouling, or oil contamination and replace at the service interval.
Common cause
Parts:spark plugs
5
Clogged or leaking fuel injector
Medium severity
An injector delivering too little or too much fuel unbalances that cylinder's mixture; injector balance testing isolates the fault.
Common cause
Parts:fuel injector
6
Vacuum leak
Medium severity
Unmetered air entering after the MAF sensor leans a cylinder or bank enough to misfire, especially noticeable at idle.
Common cause
Parts:vacuum hose
7
Low compression from worn rings/valves or cam-phaser-related valve timing wear
High severity
Mechanical wear (including cam phaser wear common on this V6/V8 family) reduces cylinder sealing or disrupts valve timing enough to prevent a clean burn; a compression/leak-down test isolates it.
Common cause
8
EGR valve fault
Low severity
A stuck-open EGR valve dumps excess exhaust gas into the intake at idle, diluting the mixture enough to cause a rough idle or misfire.
Common cause
Parts:EGR valve

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These causes are aggregated from NHTSA owner complaints and general repair knowledge — this is not a diagnosis. P0300 on your car still needs shop confirmation before any repair.

Common symptoms

Flashing or steady check engine light
Rough idle
Shaking under acceleration
Loss of power
Fuel smell from exhaust

What to check before replacing parts

Scan for cylinder-specific misfire codes

Look for: A companion P0301–P0308 pins the misfire to one cylinder — start there. P0300 with no cylinder code points at something hitting several at once: fuel pressure, a large vacuum leak, or timing.

Inspect the spark plugs and coils

Look for: Pull the plugs: black/sooty = rich, oily = oil intrusion, white/blistered = lean or overheating, cracked porcelain or an out-of-spec gap = replace. Then swap a coil to another cylinder — if a cylinder-specific code follows the coil, the coil is bad.

Check fuel trims for a vacuum leak

Look for: High positive short- and long-term trims (worst at idle, improving as RPM rises) mean unmetered air is getting in. Smoke-test the intake and listen for hissing.

Verify fuel pressure

Look for: Compare running/cranking pressure to the vehicle spec. Low or dropping pressure starves multiple cylinders and reads as a random misfire — suspect the pump, filter, or regulator.

Compression / leak-down test if ignition and fuel check out

Look for: A cylinder 15%+ below the others, or leak-down hissing from the intake (intake valve), exhaust (exhaust valve), or oil filler (rings), means the misfire is mechanical — not a swap-in part.

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Matching symptoms

Car Runs Rough Flashing Check Engine Light